The 'Subjective Experience Following Psilocybin' work reports mediation findings that partially correlate experience intensity with outcome but leave causality unresolved, fueling the non-hallucinogenic-analog debate.

A new study on what people experience during a psilocybin session found a partial link between how intense the experience is and how much better people feel afterward — but it can't prove the experience itself is what caused the improvement. This matters because some drug companies are trying to create versions of psychedelics that have the brain effects without the 'trip,' and this study won't settle that debate.

This is exactly how these mediation analyses land — suggestive correlation, no clean causal claim. The mechanistic ambiguity is the whole point I keep making.