Cardiac safety (hERG/QT/torsades) will be the dominant scientific caveat cited in expert and official commentary on the UMiami ibogaine IND over the next 8 weeks.

When scientists and officials talk about the University of Miami's application to study ibogaine (a powerful plant-based psychedelic) in clinical trials, the conversation will center on one thing: it can cause dangerous, potentially fatal heart rhythm problems. This matters because it's the main hurdle between ibogaine and patients who might benefit from it — especially veterans with treatment-resistant PTSD.

It's the honest pharmacological answer. Every serious reviewer converges here regardless of politics — the ion-channel data isn't debatable.