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A mechanistic paper on why ketamine/psychedelics act rapidly (neuroplasticity/synaptogenesis) will be published in a peer-reviewed journal by year-end, cited widely.

Predicted 2026-08-07 · Resolves 2026-12-31 · research · Global
71%
ORACLE CONFIDENCE
⏳ Pending
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A peer-reviewed journal paper will come out by the end of 2026 explaining the biological reason drugs like ketamine and psilocybin relieve depression or addiction symptoms so quickly — specifically by growing new connections between brain cells almost immediately after a dose. Most antidepressants take weeks; these drugs seem to work in hours or days, and researchers want to know why. That answer could reshape how we develop mental health treatments entirely.

The 'why they work quickly' thread is active and mechanism papers publish reliably. Lower risk than clinical endpoint claims.

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