The process for moving a drug out of the most restricted federal category starts only after the FDA approves it as medicine. Since neither psilocybin nor MDMA has reached that finish line, the DEA (the Drug Enforcement Administration) has no legal mechanism to change their status in 2026. This keeps a hard ceiling on how these substances can be used, studied, and sold across most of the country.
Scheduling follows FDA approval, not appropriations riders or public sentiment. No NDA for psilocybin or MDMA is pending final action, so DEA rescheduling is procedurally impossible in this window.