The DEA (Drug Enforcement Administration, the US agency that enforces drug laws) has been investigating online ketamine prescription services that mail ketamine to patients at home. By early 2027, at least two of those companies or high-volume prescribers are expected to face formal legal or administrative action — meaning license threats, suspensions, or settlements. This matters because it signals the era of loosely regulated at-home ketamine is ending.
Grounded in case-maturation timelines: investigations opened in 2025 reach charging/administrative-action stage in 12-18 months, landing in this window. Practice-survey data documents off-protocol prescribing at scale, supplying predicate evidence. Confidence revised DOWN from 0.74: the original framing required revocations specifically, but administrative proceedings frequently slip; the broadened action definition makes this falsifiable without overclaiming. Resolves via DEA press releases, Federal Register OSC/ISO notices, or DOJ announcements naming the registrants.