UC system (UCSF, UCLA, UCSD) will publish statistically significant psilocybin results in a non-psychiatric indication before December 2027.

University of California researchers are testing psilocybin for chronic back pain, eating disorders, and doctor burnout — and one of these trials is expected to show significant positive results before 2028.

All three running trials in non-psychiatric indications: UCSF (chronic pain, anorexia), UCLA (psilocybin+CBT adjunct), UCSD (physician burnout). At least one achieving significance within 18 months is probable given multiple concurrent trials. 76% reflects high base rate for portfolio of trials.